Product Details

Unasyn PF 1.5gm

Manufacturer: Hospira

MFG#: 00049-0013-83

NDC: 00049-0013-83

PID: 417384

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Additional Information

Product NameUnasyn PF 1.5 g
ApplicationPenicillin (Antibiotic)
Generic Drug NameAmpicillin Sodium / Sulbactam Sodium, Preservative Free
Mechanism of Action (MOA)Ampicillin inhibits bacterial cell wall synthesis; sulbactam inhibits beta-lactamase enzymes
Strength1.5 Gram
TypeIntramuscular or Intravenous
Volume10 vials per box
Onset of ActionRapid onset, typically within 30 minutes to 1 hour
Duration of ActionVaries, typically 4-6 hours depending on infection type and severity
Side EffectsRash, gastrointestinal disturbances, allergic reactions, changes in blood cell counts
Pregnancy CategoryCategory B: No known risk in human studies
ReconstitutionRequires reconstitution before use with sterile water or saline
Packaging DetailsSupplied in 1.5 g vials, 10 vials per carton
UsesTreatment of bacterial infections, including respiratory, skin, and urinary tract infections

Description

Unasyn (ampicillin sodium/sulbactam sodium) 1.5 g is a combination antibiotic formulation used for the treatment of various bacterial infections. It is indicated for the treatment of infections caused by susceptible organisms, including those affecting the respiratory tract, urinary tract, skin, and soft tissues. The formulation consists of ampicillin, a broad-spectrum penicillin-class antibiotic, and sulbactam, a beta-lactamase inhibitor.

Ampicillin works by inhibiting bacterial cell wall synthesis, leading to bacterial cell death. However, some bacteria produce beta-lactamases, enzymes that render ampicillin ineffective. Sulbactam inhibits these enzymes, allowing ampicillin to remain active against these resistant organisms.

Unasyn is administered intravenously and is typically reserved for moderate to severe infections. The usual dosage and duration depend on the severity and type of infection, as well as the patient's renal function. Side effects may include gastrointestinal disturbances, allergic reactions, and changes in blood cell counts.

Frequently Asked Questions (FAQs)

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Unasyn PF 1.5gm is manufactured by Hospira.